Penicillamine nephropathy.
نویسندگان
چکیده
منابع مشابه
Coexistent membranous nephropathy and ANCA-positive crescentic glomerulonephritis in association with penicillamine.
D-penicillamine is an effective disease-modifying drug in rheumatoid arthritis, but adverse effects are common and often lead to the cessation of treatment with this agent [1]. A variety of autoimmune disorders may be induced by the drug, either associated with organspecific autoantibodies (e.g. myasthenia gravis or pemphigus vulgaris) or with non-organ-specific autoantibodies (e.g. systemic lu...
متن کاملDermatomyositis complicating penicillamine treatment.
A case of dermatomyositis developing during the course of treatment with D-penicillamine in a patient with rheumatoid arthritis is described. Complete remission occurred on withdrawal of the drug. Possible alternative diagnoses are discussed.
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Penicillamine, dimethyl cysteine, thiovaline, remains the drug of choice for the treatment of patience with Wilson disease. It is also of value in the treatment of cysteinuria and rheumatoid arthritis, it has also been suggested that it has value in the management of other rare diseases. It also has multiple toxicities. The majority of these can be explained as chemical toxicity, for instance i...
متن کاملD-penicillamine in rheumatoid arthritis.
D-penicillamine (D-pen) has gained wide-spread use as a potent suppressor of disease activity in rheumatoid arthritis (RA) and juvenile chronic arthritis (JCA). The drug has been established for antirheumatotd therapy on the basis o f a considerable number o f comparative clinical studies o f D-pen treatment versus placebo or other disease modifying antirheumatic drugs (DMARDs). Despite the pos...
متن کامل[D-penicillamine in rheumatoid arthritis].
In view of the claim that alclofenac has a specific antirheumatoid action a detailed biochemical study has been made over a 6-month period of 2 groups of patients with rheumatoid arthritis receiving either alclofenac or D-penicillamine for the first time. We found no biochemical evidence and little clinical evidence that alclofenac had a 'penicillamine-like' effect in rheumatoid arthritis.
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ژورنال
عنوان ژورنال: Annals of the Rheumatic Diseases
سال: 1975
ISSN: 0003-4967
DOI: 10.1136/ard.34.6.544